Evidence-Based Interventions for Autism: Clinical Trials
An open-access scientific database about interventions for people with Autism Spectrum Disorder.
Our team has reviewed the scientific literature in a systematic manner to locate information on the efficacy/acceptability of interventions in people with ASD. For now, we have focused on the efficacy of psychosocial interventions.
Among all scientific papers located, we retained only the meta-analyses of controlled clinical trials. We developped strict criteria to retain the most high-quality papers from the literature.
We extracted data from meta-analytic reports in duplicate. When information was not reported in the manuscript, we contacted the team that have published the paper to obtain the missing information.
Once the data have been extracted, we have conducted the statistical analyses using an R package developped by our team. This allows to estimate - for each intervention included in the database - the pooled intervention effect on a wide range of outcomes.
We present the results of our study in this web platform. You can retrieve the list of interventions included in the database and their description in the 'interventions' sections. You can retrieve the raw results generated by our analyses in the 'database' section.
Each time we update the database with new information, we publish the approach used to arrive at these results in the scientific literature. This ensures that independent experts can give their opinion on the method used. At this time, we have only synthesized the literature on psychosocial interventions and the associated article has been published in 'Molecular Psychiatry', one of the 10 most prestigious journals in psychiatry ! (among more than 500 scientific journals)